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NFL Roundup: Big days for Manning, Brady and comebacks abound in NFL

DENVER — Peyton Manning said Wednesday that getting to the 500-touchdown mark was just “the other thing.” He got the best of both worlds on Sunday. Manning threw his 500th touchdown pass in the first quarter and finished with four TD tosses in the Denver Broncos’ 41-20 win over the Arizona Cardinals. Manning hooked up with tight end Julius Thomas for a 7- yard score on 3rd-and-goal at the 4:43 mark of the opening frame to get to the 500 milestone. He gave a mini fist pump following the touchdown. Manning finished 31-of-47 for 479 yards with two interceptions, while Demaryius Thomas had eight receptions for a career-high 226 yards and two touchdowns for Denver (3-1), which outscored Arizona 17-0 in the fourth to pull away. The five-time MVP Manning joined Brett Favre as the only other quarterback to eclipse 500 touchdown passes. Favre holds the all-time record with 508 TD tosses.