GDR Labs has launched a new liquid anti-aging supplement called Sirtuin.

By taking drops of Sirtuin daily, you can purportedly promote youthfulness, enhance overall wellbeing, and support health and longevity by stimulating the SIRT1 gene.

Find out if Sirtuin lives up to the hype today in our review.

What is GDR Labs Sirtuin?

Sirtuin is a new nutritional supplement from Game Day Ready Labs, also known as GDR Labs.

GDR Labs Sirtuin uses a blend of natural ingredients – including plant-based antioxidants – to stimulate a receptor in the body called SIRT1.

The SIRT1 receptor, according to GDR Labs, is “renowned for its ability to revitalize and maintain youthful cellular function.” By stimulating this receptor, you could promote physical and cognitive energy.

To stimulate the SIRT1 receptor, GDR Labs Sirtuin contains Japanese knotweed, a plant extract rich in resveratrol. Resveratrol is renowned for its natural antioxidant effects, and some people take Japanese knotweed daily for anti-aging, health, and wellness.

Sirtuin is priced at $63 per bottle (regular strength) or $89 per bottle (clinical strength). The formula is made in the United States from all-natural ingredients and third-party tested.

Available exclusively through GameDayReady.com

Sirtuin Benefits

Some of the benefits of Sirtuin, according to GDR Labs, include:

• Target SIRT1 and promote sirtuin activity for anti-aging power
• A blend of natural, science-backed antioxidants – including Japanese knotweed
• Increase energy and physical performance
• Improve mental clarity
• Boost cellular health
• Plant-based, all-natural formula

How Does GDR Labs Sirtuin Work?

GDR Labs offers Sirtuin in two varieties: regular strength and extra strength. However you take it, you can enjoy powerful results by activating SIRT1, a receptor linked to anti-aging effects.

Specifically, Sirtuin aims to work by:

• Activating the SIRT1 gene to enhance cellular repair and longevity
• Promoting metabolic function for overall wellbeing
• Sharpening focus, memory, and cognition
• Supporting broad anti-aging benefits across the body and mind

Some take Sirtuin because they want to feel younger. Others take it for brain health. Some take it for general health and wellness.

Sirtuin is a trademarked term created by GDR Labs. However, it’s also a molecule naturally present in the body. Sirtuin (the molecule in your body) is a nicotinamide adenine dinucleotide-dependent deacetylase. One of the isoforms of that molecule is SIRT1, which helps with sugar, fat, and energy metabolism. By taking Sirtuin (the GDR Labs supplement) daily, you can promote Sirtuin activity for anti-aging effects.

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How Sirtuin Molecules Work

Sirtuin is a family of signaling proteins best known for their effects on cell energy production.

When you take GDR Labs Sirtuin daily, you promote the activity of these signaling proteins, which helps support energy production at the cellular level.

Studies published by NIH show sirtuins can have powerful effects on the body by promoting SIRT1 activity. SIRT1 has protective effects – including antioxidant effects – while also helping to boost energy at the cellular level.

How SIRT1 Influences Aging

Age and medical conditions could decrease SIRT1 activity, lowering physical and cognitive energy.

Some people take sirtuin activator supplements—like GDR Labs Sirtuin—to help. These supplements promote SIRT1 activity, which helps to promote protective effects.

SIRT1 could influence aging via the following:

SIRT1 is a crucial molecule in glucose, lipid, and energy metabolism. It dictates your body’s energy production at the cellular level, helping your body transform sources of energy into forms you can use.

SIRT1 also has protective effects on the body, including antioxidant effects. Your body is hit with stressors every day – including stressors that cause inflammation. By taking GDR Labs Sirtuin and other Sirtuin activator supplements daily, you could promote antioxidant activity.

According to some NLM 2021 studies, SIRT1 could also help with glomerular barrier function, anti-fibrosis, and mitochondrial regulation, which is why it seems to have broad physical and cognitive effects across the body.

Overall, sirtuins influence aging through multiple pathways, from inflammation to organ protection. Some believe taking a sirtuin supplement, like GDR Labs Sirtuin, could promote anti-aging effects and help you enjoy powerful longevity effects.

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GDR Labs Sirtuin Ingredients

GDR Labs Sirtuin primarily uses Japanese knotweed to activate sirtuins. For absorption and bioavailability, GDR Labs has mixed Japanese knotweed with D-limonene and black pepper extract.

Here are all of the active ingredients in Sirtuin and how they work:

• Japanese Knotweed: The primary active ingredient in Sirtuin is Japanese knotweed 10:1 extract. Formally known as polygonum cuspidatum, Japanese knotweed has a long history of use in traditional medicine across Asia. Today, it’s best known in the supplement community as a sirtuin activator and anti-aging ingredient. Japanese knotweed is one of nature’s best sources of resveratrol, an antioxidant molecule also found in grapes and other foods.
• Instead of eating pounds of seaweed or grapes daily, you can take a Japanese knotweed extract supplement. Resveratrol is an anti-aging, antioxidant molecule also linked to sirtuin activation and SIRT1 activity, making it ideal for use in GDR Labs Sirtuin.
• Black Pepper Extract: Black pepper extract is found in many supplements for absorption. Studies show your body struggles to absorb certain plant extracts unless paired with black pepper extract. Although its mechanisms aren’t fully understood, black pepper extract can promote bioavailability and absorption, helping your body utilize more active molecules in plant extracts like Japanese knotweed.
• D-Limonene: D-limonene is a terpene in oranges, lemons, mandarins, limes, and other citrus fruits. It’s commonly added to liquid formulas to give them a pleasant, lemon-like odor. Instead of drinking concentrated Japanese knotweed, which may not taste very good, you can enjoy the flavor of lemons with each drop of Sirtuin.
• Other (Inactive) Ingredients: Sirtuin contains other inactive ingredients, including olive oil, ethyl alcohol, strawberry flavor (made from cane sugar, dextrose, fructose, and strawberry), natural flavor, and plant extractives. These inactive ingredients hold the active ingredients together, allowing them to stay stable and helping your body absorb them.

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How to Use GDR Labs Sirtuin

GDR Labs recommends placing 1mL, or around one full dropper, of Sirtuin in your mouth daily to promote longevity:

• Shake well before use
• Use the included dropper to place 1mL in your mouth and hold for 30 seconds, then swallow to ingest
• Repeat daily for anti-aging and longevity.

GDR Labs Sirtuin has a natural lemon-strawberry flavor. Some people place it underneath their tongue and take it daily for anti-aging, while others mix it with water, a shake, or the beverage they choose.

What to Expect After Taking Sirtuin

GDR Labs markets Sirtuin as everything from an anti-aging formula to a cognitive health supplement.

Here are some of the results you could experience after taking Sirtuin, according to GDR Labs:

• Strengthen Physical Performance: Sirtuin activator supplements like GDR Labs Sirtuin help your body produce energy at the cellular level. They can change how your body processes energy, helping you turn lipids (fats) and glucose (sugars) into energy your body can use. As you get older, the sirtuin activator tends to decrease, which could make you feel tired. Sirtuin can help strengthen physical performance by boosting cellular energy.
• Promote Brain Function: GDR Labs works by activating sirtuin activity. Sirtuins are enzymes linked to physical and cognitive energy. They can help your body process sugars and fats to create energy more efficiently. Some notice a change in physical energy after taking sirtuin activators like GDR Labs Sirtuin, while others see better brain function and other cognitive effects. According to GDR Labs, Sirtuin “improves mental clarity.”
• Increase Overall Energy: According to GDR Labs, Sirtuin “increases energy levels” overall. As mentioned above, the formula changes how your body processes glucose and fats into energy. When your body processes glucose and fats into energy more easily, you may feel more physically and mentally energized—especially if you’ve been dealing with age-related declines in energy.
• Support Circulation: GDR Labs Sirtuin could promote circulation and heart health. Activating sirtuins is connected to antioxidant effects, helping to neutralize free radicals that cause inflammation. Your body is hit with free radicals and other inflammatory molecules every day. Over time, inflammation increases physical symptoms of aging. Inflammation is also associated with an increased risk of disease. By taking GDR Labs Sirtuin daily, you could promote circulation.
• Boost Cellular Health: To stay healthy, your cells must transform fats and sugars into energy. Cellular health suffers if they’re unable to do this efficiently. GDR Labs Sirtuin boosts cellular health by helping your body create energy at the cellular level. Studies from the Stem Cells Journal on Wiley show that SIRT1 activation can also facilitate cellular repair.
• Enhance Cellular Repair & Longevity: As you age, your cells become damaged and must be repaired or replaced. It’s an ordinary part of aging. However, your body cannot repair itself at the cellular level as efficiently, which could lead to a growing risk of health problems. According to the manufacturer, GDR Labs Sirtuin can “help enhance cellular repair and longevity through SIRT1 activation.”
• Reinforce Youth-Promoting Functions: According to the manufacturer, GDR Labs Sirtuin can “reinforce your natural youth-promoting functions”. SIRT1 activity is associated with youthfulness and longevity. As you get older, sirtuin and SIRT1 activity tend to decline, which could lead to physical symptoms of aging. By taking GDR Labs Sirtuin daily, you could experience a significant shift.
• Can Work in Just One Day: GDR Labs claims to have conducted test groups on Sirtuin to verify it works, and those test groups found people “noticed a positive boost within the first day” of taking the supplement. Other verified purchasers notice changes within a few days or one week of taking the formula. The longer you use it, the more noticeable the benefits can be.
• No Side Effects: GDR Labs Sirtuin “is safe and side effect free,” according to GDR Labs. Unlike a drug, Sirtuin doesn’t contain synthetic chemicals or artificial ingredients; instead, it’s a blend of citrus oil, Japanese knotweed, and black pepper extract.

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Scientific Evidence for GDR Labs Sirtuin

GDR Labs Sirtuin claims to have conducted test groups on Sirtuin to verify it provides anti-aging effects. The company also cites formal scientific research as proof the formula works. We’ll review the science behind GDR Labs Sirtuin below.

One of the most cited studies on sirtuins was published in Biogerontology in 2017. Researchers found sirtuins were “a promising target in slowing down the aging process,” which is key in delaying or preventing age-related disease.

GDR Labs primarily advertises Sirtuin to activate SIRT1, a gene linked to longevity. However, researchers have identified seven members of the SIRT family in humans, including SIRT1 through SIRT7. All seven members are believed to be essential to cellular health, helping cells respond to stress, inflammation, and general aging.

It’s no secret a healthy diet and exercise program is crucial for longevity. In that same study cited above, however, researchers found a healthy diet and exercise routine increased the level of sirtuins within the body, potentially extending your lifespan. If you have a healthy diet and exercise routine, you’re likelier to engage in high sirtuin activity than someone who does not.

Science has connected sirtuin activity to lifespan, health, and aging. However, can taking GDR Labs Sirtuin increase Sirtuin activity for anti-aging effects?

The primary ingredient in GDR Labs Sirtuin is Japanese knotweed extract. A 2015 study found that Japanese knotweed was one of several natural ingredients that could influence sirtuin activity. Specifically, researchers found that Japanese knotweed was rich in an antioxidant molecule called resveratrol that could activate SIRT1, promoting antioxidant effects.

Other studies have found that Japanese knotweed contains other compounds linked to anti-aging activity. A 2021 Plants study, for example, found Japanese knotweed had several phytochemical constituents linked to antioxidant, antimicrobial, anti-inflammatory, and even anticancer effects, among other benefits.

Overall, GDR Labs Sirtuin could influence sirtuin activity using the power of resveratrol, which is naturally present in Japanese knotweed. By taking GDR Labs Sirtuin daily, you could fight back against aging at the cellular level.

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GDR Labs Sirtuin Reviews: What Do Customers Say?

Some customers were skeptical GDR Labs Sirtuin would work – only to be impressed with the supplement’s effects. We’ll summarize some of the reviews behind GDR Labs Sirtuin below.

One 80-year-old customer was “highly skeptical” GDR Labs Sirtuin would work, only to find that the supplement “peeled age right off of me.” Today, thanks to the supplement, he gets plenty of compliments from friends and family and feels younger than he has in years.

One woman claims her skin has “never looked this good” thanks to GDR Labs Sirtuin. She now feels like she’s “aging backward” because of the supplement and has plenty of energy.

Many customers notice significant results within days of taking GDR Labs Sirtuin for the first time. For example, one customer claims she felt younger within a week of taking GDR Labs Sirtuin, while another noticed a change within “after a few days.”

One verified purchaser claims to feel like she’s “40 again” because of GDR Labs Sirtuin.

Most customers find it easy to take GDR Labs Sirtuin daily. Some take it directly under the tongue, while others mix it with shakes, water, or other beverages. The formula has a light, pleasant strawberry lemon flavor.

Customers tend to have good things to say about the GDR Labs customer service team, the shipping and refund process, and other aspects of the customer experience. Generally, GDR Labs is a trusted company known for quality formulas.

GDR Labs Sirtuin Pricing

Sirtuin is priced at $63 to $89 per bottle, depending on the strength option you select. You can also save money by ordering multiple bottles of Sirtuin at once.

Here’s how pricing works when ordering GDR Labs Sirtuin online today:

Regular Strength

• 1 Bottle: $63
• 3 Bottles: $174 ($58 Per Bottle)
• 6 Bottles: $348 ($58 Per Bottle)

Clinical Strength

• 1 Bottle: $89.00
• 3 Bottles: $252 ($84 Per Bottle)
• 6 Bottles: $504 ($84 Per Bottle)

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Each bottle contains a 30-day supply of liquid formula (30 servings / 30mL). You take one full dropper (1mL) daily to promote anti-aging benefits.

To save money and ensure a steady supply of GDR Labs Sirtuin, you can also sign up for the auto-ship program and save 10%.

About GameDayReady (GDR) Labs

Sirtuin is made by GameDayReady (GDR) Labs, a US-based supplement company best-known for its lineup of anti-aging liquid formulas.

From its headquarters in Alpharetta, Georgia, GDR Labs produces popular formulas like Conolidine, Nutra IGF, Gabasom, and Liponine, among others. Some are designed for broad anti-aging benefits, while others are built specifically for weight loss or other targeted effects.

You can contact GDR Labs and the Sirtuin customer service team via the following:

• Phone: 629-276-4922
• Mailing Address: 1360 Union Hill Road, Alpharetta, GA 30004

Under American Laboratories and Logistics, LLC, GDR Labs manufactures supplements in Alpharetta, Georgia.

Final Word

Sirtuin is an anti-aging liquid formula created by GDR Labs.

By taking drops of Sirtuin daily, you can purportedly activate a class of enzymes called sirtuins within your body, helping to promote anti-aging benefits using the power of resveratrol-rich Japanese knotweed extract.

Visit the official GameDayReady website to learn more about Sirtuin and how it works, or buy the popular liquid Sirtuin activator today.