What Is Dulaglutide?

People suffering from conditions like Type 2 diabetes often gain a lot of weight. While there can be several friends that accompany such gains, the main ones happen to be the lack of insulin sensitivity and high blood sugar levels.

Type 2 diabetes can affect the production of the GLP-1 hormone in your digestive system, and prescription medications like Dulaglutide aim to help balance out the same. This injective medication acts as a synthetic substitute for this hormone and has helped several Type 2 diabetic patients achieve healthy blood sugar levels and overall health goals.

Dulaglutide comes in the form of injections and is supposed to be taken once a week. Although its main function is to balance the hormonal production of your body, one of the most prominent consequences of this product happens to be fast weight loss.

However, you must get a prescription before purchasing Dulaglutide, as it is not suitable for everyone. Even though several influencers and organizations may market this product as a weight loss assistant, it has not been created for this purpose. This is why if you are not suffering from Type 2 diabetes, it is best to stay away from Dulaglutide.

What’s The History Of Dulaglutide?

The U.S. Food and Drug Administration (FDA) approved dulaglutide for the treatment of type 2 diabetes. However, due to potential risks associated with the medication, the FDA implemented a Risk Evaluation and Mitigation Strategy (REMS) for dulaglutide.

This strategy includes specific steps that the pharmaceutical company, Eli Lilly, must take to ensure physicians are aware of the risk of pancreatitis and the potential risk of medullary thyroid carcinoma associated with the drug.

In 2020, the FDA granted approval for two higher doses of dulaglutide, namely 3.0 mg and 4.5 mg. This approval was based on the results of the AWARD-11 trial, which demonstrated the improved glucose-lowering and weight benefits of these higher doses. These new doses provide additional options for healthcare providers to tailor the treatment to individual patient needs.

But what are the deadly side effects that make Dulaglutide such a dangerous option for people looking to lose a few pounds?

What Are The Side Effects Of Dulaglutide?

If you visit the official website of Dulaglutide, you will find that there is a huge list of common side effects. They are outlined very clearly, and believe us when we say – it is not a brief compilation!

For starters, routine use of Dulaglutide injections can lead to thyroid tumors and cancer, which is why you must look out for its symptoms constantly. It may also inflame your pancreas, lower your blood sugar to a dangerous level, and cause stomach issues as well.

Your body may also go through a series of allergic reactions while you are on your Dulaglutide cycle, your vision may get blurred, and your kidney may get damaged. Further, let’s just say that this is only the tip of the iceberg – you can experience several other side effects depending on your health condition as well.

What Are The Top Dulaglutide Alternatives?

With so many side effects outlined in the previous section, you must be wondering – are these problems worth the results that Dulaglutide provides us with? Well, the answer to this question lies with your medical situation.

Do you want to use Dulaglutide because you have Type 2 diabetes, or simply because you want to use a lot of weight quickly?

If the answer is the latter option, we strongly recommend you check out the following safe alternatives:

• PhenQ
• Phen24
• PhenGold
• TrimTone
• PrimeShred

PhenQ

PhenQ is one of the most popular weight loss supplements out there on the market today. It has been created for both men and women who wish to get rid of the excess fat in their body, but do not want to rely only on working out or dieting. It has a 5-in-1 formula and consists of several natural ingredients that amplify the benefits of PhenQ.

The weight loss pills are so effective because they consist of the unique and patented A-lacy’s reset formula. This formula has been clinically proven to help prevent fat accumulation in the body and destroy fat cells at the same time.

The core ingredients of PhenQ have also been found to be effective in terms of detoxifying the body from within and supplying it with an adequate amount of antioxidants too. This way, your body will function properly.

You can also feel higher energy levels and better cognitive health after consuming the PhenQ weight loss supplement.

Pros Of PhenQ

There are several pros of PhenQ, such as:

• Natural ingredients and Lacy’s reset formula used to create the supplement
• No side effects were reported by a majority of PhenQ reviews
• Can reduce appetite, thus aiding your fat loss journey
• Can boost metabolism

Cons Of PhenQ

There are a few cons of PhenQ as well, like:

• High caffeine concentration might interfere with your sleep patterns if you consume PhenQ after 3-4 pm

Phen24

If you belong to the group of people who do not like it when their weight loss supplement only works for a few hours a day to burn fat, Phen24 might be a great fit for you. The creators of this product devised its formula in a way that helps individuals burn fat during the day and accelerates the entire process as they sleep too.

Basically, you take one pill in the morning with a glass of water. It fuels your body from within – providing you with higher energy levels, better cognitive function, and a faster fat-burning process.

Then, about 15 minutes after your dinner, you take two capsules together with another glass of water. This dosage helps you sleep more soundly while burning the fat in your body. As nighttime is the duration when your entire body rejuvenates and replenishes, it is the ideal time for destroying the fat cells too.

According to several Phen24 reviews, users of this supplement have found it to be helpful in suppressing sugar and junk food cravings as well. Hence, you may find it easier to stick to a more nutritious and healthy diet once you start consuming this weight loss supplement routinely.

Pros Of Phen24

There are several pros of Phen24, including but not limited to:

• Unique formula that helps burn fat during the day as well as at night
• Helps decrease the buildup of fat
• Reduces cravings
• Boosts energy

Cons Of Phen24

The cons of Phen24 are:

• The creators of Phen24 suggest taking 3 pills a day, which might be excessive for some people

PhenGold

If you are a fitness enthusiast who is looking to begin cutting, PhenGold is a great option to consider. The natural ingredients of this supplement help you lose weight without causing any harmful side effects in your body, which can help you achieve your fitness goals much more efficiently.

The multi-action formula of PhenGold is ideal for both newbies who want to start their fat loss journey and experienced individuals who have done it before. It consists of clinically-backed ingredients that are effective in helping people reduce fat accumulation, which is why many people have put their faith in the product as well.

One of the major ways through which PhenGold burns fat is by accelerating your metabolism. Since it is the rate at which your body converts food into fuel, boosting it can lead to less fat storage and higher energy levels at the same time.

Further, it is common to have frequent mood swings while one is on a fat loss journey. This is why the creators of PhenGold decided to include mood enhancers in its formula that can have a calming effect on the brain and help you focus more, such as caffeine.

Pros Of PhenGold

A few of the several pros of PhenGold are:

• Orders are shipped for free all around the world
• The formula of PhenGold is manufactured in an FDA-registered facility
• Can help you achieve your weight loss goals
• Clinically proven ingredients used
• No potential side effects

Cons Of PhenGold

A few cons of PhenGold are:

• You must combine PhenGold with the right amount of dieting and workout plans to see visible results

TrimTone

If you are looking for a fat-burning supplement that has been created to suit the needs of women specifically, you must try out TrimTone. The creators of this weight loss supplement have used only the most effective and natural core ingredients to formulate it to burn fat throughout the day.

TrimTone can help burn body fat and reduce appetite at the same time. This means that while your body will be getting rid of the stubborn fat cells, you will not be supplying it with unnecessary fats – thus keeping you on track with your weight loss journey.

It also has several sources of caffeine, such as coffee and tea, which can help increase your alertness and keep you energetic throughout the day. All these benefits of TrimTone combine to provide users with an effortless process of maintaining their health.

Pros Of TrimTone

A few of the several pros of TrimTone are:

• Made for women
• Only needs to be consumed once a day
• Free delivery on any package
• The ingredients used in TrimTone formula are GMP-certified

Cons Of TrimTone

The drawbacks of TrimTone are:

• Not suitable for vegans

PrimeShred

If we included a weight loss supplement for women, how can we forget the men? Primshred has been created for athletic men who wish to experience a fast, easy, yet effective fat-loss journey to achieve a more shredded look. While most supplements rip the body off of its energy, PrimeShred ensures that your muscle stays intact as you get rid of the excess fat.

The creators of PrimeShred created a formula that is highly potent in terms of helping men achieve their peak physique. When combined with an effective diet and a passionate workout routine, PrimeShred can do wonders for your body – at least that’s what the majority of reviews of this supplement say!

PrimeShred mainly works by boosting the metabolism in your body and activating the hormones that burn fat. This way, it is your body that is burning the fat – PrimeShred is just prompting it. Hence, the weight loss supplement has little to no side effects on the body.

Pros Of PrimeShred

The pros of PrimeShred are as follows:

• Made for men who want to achieve a shredded look
• Helps lose fat without loss of lean muscle gain
• Suitable for vegans
• Non-GMO

Cons Of PrimeShred

A few cons of PrimeShred are:

• According to a few reviews of PrimeShred, the weight loss supplement is said to have caused mild headaches and nausea

What Are The Clinical Studies Backing Dulaglutide Alternatives?

A group of researchers searched for studies that investigated the impact of guarana on weight loss. They selected randomized controlled trials (considered the gold standard in research) that compared guarana supplementation to a placebo or control group. The studies included both men and women, with varying ages and body mass indexes (BMIs).

After a thorough search, the researchers identified 10 eligible studies with a total of 1,000 participants. These studies ranged in duration from 4 to 12 weeks. The researchers extracted data on weight loss outcomes, including the percentage of body weight lost and changes in BMI.

Upon analyzing the combined data, the meta-analysis revealed promising results. On average, individuals taking guarana lost 2.5% more body weight than their counterparts who did not receive the supplement.

Another study conducted by researchers from a renowned university in 2020 aimed to investigate the effects of chromium picolinate supplementation on body weight and composition in overweight and obese individuals. The study included a diverse group of participants, ranging from different age groups to varying levels of physical activity.

After a carefully monitored period of 12 weeks, the researchers collected data on body weight, body mass index (BMI), body fat percentage, and waist circumference from both groups. They then analyzed the data using statistical methods to determine the effectiveness of chromium picolinate.

What Are The Medical Uses Of Dulaglutide?

Dulaglutide is primarily used as a medication for adults with type 2 diabetes mellitus. It is prescribed as an adjunct to diet and exercise in order to improve glycemic control. However, it is important to note that dulaglutide is not indicated for the treatment of individuals with type 1 diabetes mellitus or those with diabetic ketoacidosis.

This is because these conditions result from the inability of islet cells to produce insulin, whereas dulaglutide works by stimulating functioning islet cells to produce more insulin.

Combination Therapy

Dulaglutide can be used as a stand-alone treatment or in combination with other medications for type 2 diabetes. It is often prescribed alongside metformin, sulfonylureas, thiazolidinediones, and insulin, particularly when taken concomitantly with meals.

The combination therapy approach aims to further enhance glycemic control and manage the condition effectively.

Efficacy and Weight Loss

Clinical trials conducted during the medication’s phase 3 program have shown promising results. The trials demonstrated that dulaglutide, at doses of 0.75 mg and 1.5 mg, resulted in reductions in hemoglobin A1c levels of approximately 1%. Additionally, on average, patients experienced weight loss of around 5 pounds.

Higher doses of 3.0 mg and 4.5 mg, approved more recently in 2020, exhibited even greater reductions in hemoglobin A1c levels, closer to 1.5%, along with slightly more weight loss.

Safety and Mortality

A meta-analysis conducted in 2017 investigated the safety of GLP-1 agonists, including dulaglutide, and DPP-4 inhibitors in the treatment of type 2 diabetes. The study found no evidence to support the suggestion that these medications increased all-cause mortality in individuals with type 2 diabetes.

This analysis provides some reassurance regarding the safety profile of dulaglutide and its potential benefits in managing the condition.

Final Verdict: Dulaglutide Alternative

Dulaglutide, approved by the U.S. FDA, is primarily intended for managing type 2 diabetes by improving glycemic control. It stimulates the production of insulin by functioning islet cells, making it effective for individuals with this condition.

While some may be enticed by the prospect of weight loss associated with Dulaglutide, it’s important to remember that this medication was not developed for weight management, and its use should be under medical supervision.

The potential side effects, such as thyroid tumors, pancreatitis, and severe allergic reactions, underscore the need for caution.

Considering these factors, if you are not dealing with type 2 diabetes, it is advisable to explore safer alternatives for weight loss. Several products like PhenQ, Phen24, PhenGold, TrimTone, and PrimeShred offer effective weight management solutions without the potential risks associated with Dulaglutide.

These supplements incorporate natural ingredients and tailored formulas designed to help you achieve your health and fitness goals.