GenuinePurity’s Fisetin is a new nutritional supplement designed to protect against oxidative stress, cellular damage, and inflammation.
By taking two capsules of Fisetin daily, you can purportedly support healthy aging using a clinical dose of a single science-backed ingredient: fisetin.
Find out everything you need to know about GenuinePurity’s Fisetin and how it works today in our review.
What is GenuinePurity Fisetin?
GenuinePurity Fisetin is a senolytic supplement designed to clear aging cells and support anti-aging benefits.
Available exclusively through the GenuinePurity online store, Fisetin contains a single active ingredient – fisetin – to promote its active effects.
Each capsule of GenuinePurity Fisetin contains 150mg of fisetin to support healthy inflammation, protect against oxidative stress, and defend the body against cellular damage, among other benefits.
GenuinePurity manufactures Fisetin primarily to customers interested in anti-aging benefits. As you get older, your body doesn’t recycle aging cells as effectively, leading to an increased risk of disease and illness and sapping your longevity. GenuinePurity’s Fisetin aims to promote longevity using a science-backed ingredient.
GenuinePurity is a health and wellness brand and subsidiary of Leading Edge Health, a British Columbia-based supplement company. The company manufactures supplements in the United States in FDA-registered, GMP-certified facilities.
GenuinePurity Fisetin Benefits
According to GenuinePurity, Fisetin can promote benefits like:
- Protect against oxidative stress
- Defend the body against cellular damage
- Reduce inflammation
- Promote senolytic effects to clear aging cells
- Enhance healthspan and lifespan
- Backed by 97-day moneyback guarantee
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How Does GenuinePurity Fisetin Work?
GenuinePurity Fisetin works by delivering a strong dose of quercetin directly into your body. Plus, the supplement uses liposomal encapsulation technology to protect the active ingredient and ensure it gets absorbed into your system.
By taking one or two capsules of GenuinePurity Fisetin daily, you’re giving your body 150mg to 300mg of fisetin to promote various physical and cognitive effects.
Fisetin is known as a “senolytic” compound. That means it encourages your body’s process of clearing away old, aging cells.
As you age, some of your cells become old and die. Your body replaces these cells with newer, younger cells. It’s a natural process occurring frequently within your body.
By taking GenuinePurity Fisetin, you can purportedly kickstart your body’s senolytic processes, helping you turnover old cells and replace them with newer ones.
By taking one or two capsules of GenuinePurity Fisetin daily, you can purportedly enjoy effects like:
- Defend against cellular damage.
- Reduce harmful inflammation.
- Improve cognitive function.
- Enhance health span and overall lifespan.
In fact, GenuinePurity describes fisetin as “the world’s most powerful senolytic.” In one study, researchers tested 10 flavonoids and found fisetin was the most potent.
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GenuinePurity Fisetin Ingredients
GenuinePurity Fisetin contains a single active ingredient: fisetin. Each capsule contains 150mg of fisetin, giving you 300mg of fisetin total per day.
Fisetin: Fisetin is a natural molecule found in certain fruits and vegetables. Recent research has revealed the molecule has powerful effects against aging cells. Specifically, fisetin appears to target malfunctioning “zombie” cells that refuse to die. By encouraging newer cells to replace these zombie cells, fisetin can help defend your body against the effects of aging. Fisetin is naturally present in onion, grape, cucumber, apple, persimmon, and strawberry. It’s a flavonoid, or plant-based antioxidant, that appears to work more effectively than other popular flavonoids available today.
Other, inactive ingredients within GenuinePurity Fisetin include vegetable cellulose (to create the capsule), microcrystalline cellulose, maltodextrin, phospholipid complex (with sunflower lecithin and phosphatidylcholine), silicon dioxide, and vegetable stearate.
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What Does Fisetin Do?
The active ingredient in GenuinePurity Fisetin is, understandably, fisetin. There are no other active ingredients.
Here’s how the active ingredient within GenuinePurity Fisetin works:
Reduce Zombie-Like Cells to Promote Longevity: The primary goal of fisetin is to reduce zombie-like cells, promoting longevity. Your body is filled with zombie-like cells that refuse to die. These cells can make you feel older than you really are. They contribute to lethargy and make you feel physically and cognitively weak. One of the primary goals of fisetin is to reduce zombie cells. As proof, GenuinePurity cites one study where fisetin reduced zombie-like cells in the fat tissue of youthful mice within 5 days.
Neutralize Stubborn Cells for Recycling: Some zombie cells refuse to be recycled – even if they’re no longer active. GenuinePurity Fisetin is designed to neutralize these stubborn cells to improve wellness and extend lifespan.
Reverse Decades of Damaged Cell Buildup: When zombie cells refuse to die, they build up over time. Your body can’t recycle these cells, leading to decades-long buildup. You might feel older than your actual age because of this excessive buildup of zombie cells.
Recycle Malfunctioning Cells: When cells enter a zombie-like state, they’re no longer functioning like they’re supposed to. These malfunctioning cells contribute to health problems, low energy, and general health and wellness issues. By taking GenuinePurity Fisetin daily, you can recycle these malfunctioning cells for superior results.
Support Antioxidant Effects: Your body is bombarded by oxidation every day. This oxidation causes visible signs of aging. GenuinePurity Fisetin provides antioxidant effects, neutralizing the free radicals that cause inflammation. By neutralizing these free radicals, GenuinePurity Fisetin can promote healthy inflammation throughout the body, helping you fight back against harmful compounds. Higher levels of inflammation are linked to a higher risk of disease and illness, and controlling inflammation can help mitigate this risk.
Boost Cellular Defense: According to GenuinePurity, fisetin can promote cellular defense by switching on antioxidant enzymes and boosting the activity of existing enzymes. By defending your body at the cellular level, GenuinePurity Fisetin can promote powerful anti-aging effects.
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Safeguard Mitochondria: GenuinePurity claims its Fisetin can safeguard mitochondria. Mitochondria create energy for every cell in your body. These mitochondria can also be impacted by oxidative stress or inflammation. GenuinePurity Fisetin can safeguard mitochondria, helping to preserve the cellular infrastructure for improved well being.
Naturally Reduce Inflammation: Many of the benefits of GenuinePurity Fisetin revolve around reducing inflammation. By taking GenuinePurity Fisetin daily, you can reduce inflammation. Fisetin has natural antioxidant properties, which means it can help neutralize the free radicals that cause inflammation. According to GenuinePurity, Fisetin can reduce inflammation by:
Inhibiting the production of pro-inflammatory cytokines and enzymes, which are your body’s natural ways to reduce and control inflammation.
Modulate pathway interference, hindering specific chains linked to inflammation. Specifically, fisetin has been shown to obstruct the activation of nuclear factor-kappa B, affecting your inflammatory response. In layman’s terms, fisetin can interrupt the chain reaction of processes that lead to inflammation in the first place.
Promote enzyme expression edging, restricting pro-inflammatory prostaglandins and leukotrienes linked to inflammation.
Protect & Promote Brain Function: GenuinePurity Fisetin can purportedly protect and promote brain function. Fisetin has natural neuroprotective effects. Some believe these effects are linked to the natural antioxidant properties of fisetin, which work throughout the brain and body. According to GenuinePurity, Fisetin can also promote brain function by:
Promoting brain plasticity, helping the brain respond to damage and stimuli at all ages.
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Promote overall neurological enhancements, including the generation of brain-derived neurotrophic factor, which helps neurons (brain cells) connect more effectively.
Promote anti-clumping effects, inhibiting the clustering of beta amyloid plaque, one of the main signs of degenerative brain diseases like Alzheimer’s and dementia. The more beta amyloid plaque is in your brain, the more neurological disharmony you accumulate.
Promote cellular signaling streams linked to brain processes. According to GenuinePurity, Fisetin could impact diverse cellular signaling streams involved in synaptic learning, neuronal endurance, and intellect while also interacting with the mTOR pathway associated with intelligence. That’s a fancy way of saying fisetin promotes overall brain activity in multiple ways, helping you feel smarter and more cognitively energized.
Support Cardiovascular Health: Some take fisetin specifically for heart health. According to GenuinePurity, Fisetin can promote cardiovascular health by interacting with cholesterol, vessel dilation, and even your blood’s ability to clot, among other factors:
Lipid lifting, positively shaping lipid profiles to reduce total cholesterol, unhealthy LDL cholesterol, and triglycerides while boosting “good” HDL cholesterol.
Dilating vessels, helping to boost circulation and moderate blood pressure to guard cardiovascular function.
Anti-clotting activity, helping to avoid the overzealous clumping of fibrinogens that could lead to heart attacks, strokes, and other dangerous cardiovascular events.
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Extend Health & Promote Longer Lifespan: Many people take GenuinePurity Fisetin simply to extend health and promote a longer lifespan. The ingredient works in various ways to promote longevity – from controlling inflammation to supporting cardiovascular health. However, it also interacts with your body at the cellular level to promote a longer lifespan within each cell via effects like:
Senolytic effects to eliminate old, senescent cells. Aging cells entire a zombie-like state where they no longer function as they’re supposed to or duplicate. Fisetin appears to promote senolytic effects to recycle old, senescent cells from the body.
Promote cellular health by boosting mitochondrial function. Healthier, longer-living people tend to have healthier mitochondria than unhealthy people. GenuinePurity Fisetin can promote longevity at the cellular level by targeting mitochondria function.
Defend DNA, helping to protect DNA against oxidative stress and inflammation. Your DNA is bombarded by oxidative stress and inflammation daily, leading to aging DNA. Aging DNA has worse chromosomal activity and a greater risk of mutations, potentially leading to health issues. Fisetin could help.
Works Without Side Effects: While other anti-aging supplements and medications can lead to side effects, GenuinePurity Fisetin works without side effects. Studies show fisetin is not expected to lead to significant side effects in healthy adults. It’s been well-tolerated in most trials to date.
Because of all of these effects, GenuinePurity has designed Fisetin to be the ultimate anti-aging supplement. It works on multiple pathways to defend your body against the effects of aging at the cellular level.
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How GenuinePurity’s Liposomal Encapsulation Technology Works
There are other fisetin supplements available today. One thing that makes GenuinePurity’s Fisetin unique, however, is the use of liposomal encapsulation technology.
GenuinePurity uses a protective “liposome,” or fatty layer, to create a protective shield around the active ingredients. This protective layer defends the active ingredients against your stomach acid, allowing them to pass through unharmed to reach your digestive tract.
According to GenuinePurity, the company’s liposomal encapsulation technology provides benefits like:
Liposomal Benefit #1: Preserves Integrity of Ingredients Against Stomach Acid: Forms a safeguarding shield to protect your fisetin from stomach acid, allowing more of the active ingredients to enter your digestive tract and be absorbed. It preserves the integrity of these ingredients even as your stomach acid tries to destroy them.
Liposomal Benefit #2: Amplifies Solubility: The liposomal layer amplifies the solubility of the active ingredients, which makes the ingredients easier for your body to absorb. When ingredients are smaller and more soluble, they’re easier for your body to absorb, which means more of the active ingredients enter your bloodstream.
Liposomal Benefit #3: Elevates Uptake at the Cellular Level: Finally, the liposomal layer elevates cellular uptake by facilitating liposomal fusion with cell membranes, helping the fisetin enter your cells at the best possible rate. The liposomal layer ensures the fisetin is delivered directly into your cells, elevating cellular uptake.
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GenuinePurity Fisetin vs. Fake Fisetin
There are other fisetin supplements available today. However, some fisetin supplements – even those from popular brands – contain fake fisetin, which isn’t very effective.
Here’s how GenuinePurity explains the dangers of fake fisetin:
Many popular supplements claim to contain fisetin, but they actually contain very little fisetin when checking these supplements with a lab.
Many products contain zero fisetin whatsoever, for example. These products are advertised as fisetin supplements and claim to support healthy aging. As soon as labs tested the supplements, however, they found there’s no fisetin inside.
Other products contain much less than the advertised dose of fisetin. You might have paid a premium for a strong fisetin supplement, only to be getting less fisetin than you realized.
To combat fake fisetin, GenuinePurity provides a certificate of analysis with every formula – including all Fisetin purchases. This certificate of analysis verifies the formula contains exactly what it’s supposed to contain, ensuring you receive the fisetin you intended to purchase.
Scientific Evidence for GenuinePurity Fisetin
GenuinePurity cites dozens of scientific studies on the official Fisetin website, including double-blind, placebo-controlled clinical trials published in peer-reviewed medical journals. Many of these studies show fisetin works as advertised to promote the benefits listed above – including longer lifespan, healthier aging, and senolytic effects. We’ll review some of the science behind GenuinePurity Fisetin below.
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One of the most frequently cited studies on fisetin was published in Antioxidants in 2024. Researchers tested the effects of fisetin on cellular senescence. They wanted to see if fisetin could genuinely promote cellular renewal. They applied fisetin to the tissues and organs of old sheep, then watched the effects. Researchers found “fisetin treatment significantly decreased senescent neurons, astrocytes, and microglia” throughout the brain of the sheep while also promoting senescent effects in other organs. Prior to fisetin treatment, these tissues were old and covered with aging cells. Because of these effects, researchers concluded fisetin “represents a promising therapeutic strategy for age-related diseases.”
Some studies have specifically connected fisetin to a longer lifespan. In a 2018 study, for example, researchers found fisetin was a “serotherapeutic that extends health and lifespan.” Researchers tested 10 flavonoids and found fisetin was the most potent for extending lifespan and promoting senescence. In other words, fisetin promoted cellular renewal much more effectively than the other tested flavonoids. All flavonoids have antioxidant effects that could promote cellular renewal, but fisetin was particularly potent.
Other studies have connected fisetin to brain health and neuroprotective effects. A 2024 study, for example, found fisetin could protect against oxidative stress – particularly in brain tissue. Researchers found fisetin interacted with brain tissue at the molecular level to promote a better inflammatory response and adaptogenic effects.
Finally, one comprehensive study analyzed the effects of fisetin on inflammation, aging, and age-related diseases in roundworms. Researchers gave fisetin or a placebo to roundworms, then exposed them to oxidative stress (via UV irradiation). Researchers found fisetin significantly reduced free radical activity in roundworms, helping the roundworms live longer. Researchers also found evidence fisetin could protect against Parkinson’s disease.
Overall, recent research has increasingly validated the effects of fisetin, showing it could have powerful anti-aging effects. By taking GenuinePurity’s Fisetin daily, you could support all of the advertised effects listed above, based on current scientific evidence.
GenuinePurity Fisetin Pricing
GenuinePurity Fisetin is priced at $59.95 per bottle. The more bottles you buy, the more you can save.
Here’s how much you pay when ordering GenuinePurity Fisetin online today through the official website:
- 1 Bottle: $59.95
- 3 Bottles: $159.95 ($53.32 Per Bottle)
- 6 Bottles: $159.75 ($26.63 Per Bottle)
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Each bottle of GenuinePurity Fisetin contains a 30 day supply of Fisetin, or 60 capsules (60 servings). You take one or two capsules daily to promote longevity.
GenuinePurity Fisetin Refund Policy
GenuinePurity Fisetin has a 97-day moneyback guarantee. You have 97 days from the date of purchase to try the supplement, decide if you like the effects, then request a complete refund if you’re unhappy for any reason. You receive a complete refund even if the bottles are empty.
About GenuinePurity
GenuinePurity is a nutritional supplement company specializing in longevity supplements. The company is known for offering a range of anti-aging supplements and similar formulas.
In addition to Fisetin, popular supplements from GenuinePurity include Resveratrol, Liposomal NMN, and Nicotinamide Riboside, among others. The company offers supplements designed to fight aging on a cellular level, optimize lifespan, and use science-backed ingredients for targeted effects.
You can contact GenuinePurity for questions and concerns about Fisetin via the following:
- Online Form: https://www.genuinepurity.com/contact-us/
- Phone: 1-866-968-6643
GenuinePurity is a subsidiary of Leading Edge Health, a British Columbia-based health and wellness company offering a range of supplements and formulas targeting different goals. The company also maintains a registered address in Limassol, Cyprus.
Final Word
Fisetin has surged in popularity in the anti-aging supplement community over the last decade.
Today, growing research shows fisetin can promote anti-aging effects at the cellular level, reducing inflammation and encouraging the recycling of aging cells.
GenuinePurity has made it easy to get a strong daily dose of fisetin. Each capsule of GenuinePurity Fisetin contains 150mg of fisetin to promote anti-aging effects at the cellular level.
