GenuinePurity Spermidine is an autophagy activator designed to promote anti-aging benefits at the cellular level.
Taking two capsules of GenuinePurity Spermidine daily promotes cellular renewal and activates your body’s natural autophagy, or cellular recycling, processes.
Does GenuinePurity Spermidine work? How does the supplement help with aging? Keep reading to find out everything you need to know about GenuinePurity Spermidine and how it works today in our review.
What is GenuinePurity Spermidine?
GenuinePurity Spermidine is a nutritional supplement made from 99% pure spermidine.
Spermidine is a natural ingredient that promotes cellular renewal, making it a popular anti-aging supplement. The use of spermidine has surged in recent years, with many taking spermidine supplements daily for anti-aging benefits.
To maximize the effects of spermidine, GenuinePurity has encapsulated the active ingredient in a liposomal capsule, wrapping it in fatty layers to ensure the highest possible dose gets absorbed into the body.
GenuinePurity Spermidine is exclusively available through the GenuinePurity online store, where it’s priced at $60 per bottle and backed by a 97-day money-back guarantee.
GenuinePurity Spermidine Benefits
Some of the benefits of GenuinePurity Spermidine, according to the manufacturer, include:
- Activate autophagy(natural cellular renewal)
- Made with wheat germ extract with zero synthetic ingredients
- Promotes healthy aging and longevity
- Supports heart health, metabolism, cellular energy, and more
- Liposomal encapsulation for maximum absorption and effectiveness
- Backed by 97-day moneyback guarantee
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How Does GenuinePurity Spermidine Work?
GenuinePurity recommends taking two capsules of Spermidine daily, preferably with meals, for optimal results.
Each capsule of GenuinePurity Spermidine contains a single active ingredient: 99% pure spermidine. Spermidine is derived from wheat germ extract, making it a natural ingredient with no known side effects.
According to GenuinePurity, Spermidine can promote benefits like:
- Promote cellular renewal
- Reduce inflammation
- Promote healthy aging and longevity
Studies show autophagy is closely linked to longevity. Autophagy is the process your body uses to cleanse old cells and replace them with new, young, healthy cells. When your body has a high level of autophagy, you’re eliminating old cells rapidly and replacing them with new cells, helping to boost energy and support anti-aging benefits throughout the body.
As you get older, your cellular renewal rate tends to decrease. Your autophagy rate decreases, causing more old cells to build up in your body. This can lead to noticeable effects of aging – like low energy, imbalanced hormones, mental fog, and more.
GenuinePurity Spermidine aims to help by inducing autophagy, kickstarting your body’s natural cellular renewal process.
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What Does GenuinePurity Spermidine Do?
GenuinePurity Spermidine provides a range of active effects – from extending your lifespan to promoting healthy inflammation.
Here are some of the benefits of spermidine and what it does after entering your body:
Extends Lifespan: Autophagy is the natural bodily process of recycling damaged or malfunctioning cells, replacing them with new, young, and healthy cells. GenuinePurity cities ample scientific evidence that spermidine “has been shown to induce autophagy,” which could help remove dysfunctional elements and boost cellular health.
Anti-Inflammatory: GenuinePurity Spermidine has anti-inflammatory effects, according to GenuinePurity. Long-term inflammation is associated with an increased risk of disease and illness. According to GenuinePurity, which again cites scientific evidence, “spermidine has been suggested to support healthy anti-inflammatory function” while contributing to overall health and longevity.
Supports Mitochondrial Function: Mitochondria are the powerhouses of the cells, and they create energy at a cellular level throughout your body. GenuinePurity says spermidine “has been linked to improved mitochondrial function.” Improved mitochondrial function can lead to greater physical and cognitive energy, boosting energy in every cell of the body.
Improves Cardiovascular Function: The spermidine in GenuinePurity Spermidine could improve cardiovascular function, according to GenuinePurity, which cites several studies – including a study published by the American Heart Association. In these studies, spermidine was shown to promote cardiovascular benefits like:
- Support blood vessel function
- Anti-inflammatory effects
- Antioxidant properties
Enhances Metabolic Health: Metabolic health refers to how your body produces energy, maintains weight, supports blood sugar, and supports overall homeostasis. In GenuinePurity Spermidine, the active ingredient can purportedly help with polyamine catabolism, benefiting metabolic pathways. That’s a fancy way of saying it promotes blood sugar balance, weight management, and overall health.
Promotes Autophagy & Cellular Health: When your cells are old, sick, and damaged, they’re not performing at their best. GenuinePurity Spermidine reverses this issue by promoting autophagy and boosting cellular health. By encouraging your body to recycle old cells, spermidine can support anti-aging benefits and boost health at the cellular level, helping to impact every part of your body and mind.
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Promotes Insulin Sensitivity: Spermidine “may influence insulin sensitivity,” according to GenuinePurity. The company cites studies that show improved insulin sensitivity was associated with better glucose metabolism and a reduced risk of insulin resistance.
Activates AMPK: AMP-activated protein kinase, or AMPK, is an enzyme linked to energy production at the cellular level. Several scientific studies show spermidine can activate AMPK, enhancing glucose uptake and fatty acid oxidation. That’s a fancy way of saying spermidine can help with weight loss, blood sugar balance, and energy.
Supports Cognition: GenuinePurity Spermidine can purportedly support cognition and brain health in multiple ways. Autophagy plays a critical role in brain health. If your brain is filled with old, damaged cells, it won’t function as it should. Taking a spermidine supplement daily can replace old brain cells with new ones, boosting cognitive energy overall. It can also induce neurogenesis or the production of new brain cells (neurons). Overall, GenuinePurity claims Spermidine can promote cognitive health in three separate ways, including:
- Autophagy, or the natural recycling of old brain cells
- Neurogenesis, or the production of neurons
- Support for neurological health overall
Suppression of Inflammatory Signaling Pathways: We discussed GenuinePurity Spermidine’s anti-inflammatory effects above. However, the formula also has additional anti-inflammatory effects. According to GenuinePurity, the supplement can help with inflammation via the following:
- Suppressing inflammatory signaling pathways
- Inducing autophagy, helping to recycle inflamed cells
- Inhibiting inflammatory mediators
Helps Increase Longevity: Inducing autophagy could help you live longer. As you get older, autophagy declines. Your body doesn’t replace as many old cells as it used to, leading to noticeable effects of aging. According to the manufacturer, you could reverse this decline by taking a spermidine supplement like GenuinePurity Spermidine. In a chart, GenuinePurity shows spermidine levels increasing with age with the use of the supplement – not declining as you would generally expect them to.
GenuinePurity Spermidine Ingredients
GenuinePurity Spermidine contains a single active ingredient: 99% pure spermidine derived from wheat germ extract.
Here’s the sole active ingredient in GenuinePurity Spermidine and how it works:
99% Pure Spermidine from Wheat Germ Extract: Spermidine, a natural polyamine, induces autophagy, your body’s natural cellular renewal process. The cells in your body degrade over time and need to be recycled and replaced with new cells. When your body can’t induce autophagy, you end up with too many damaged, old cells that aren’t functioning correctly. Spermidine induces the autophagy process, contributing to overall well-being and longevity.
Phospholipid Complex & Liposomal Delivery System: GenuinePurity wraps the active ingredient in a liposomal delivery system, surrounding it with fatty acids (like a phospholipid complex derived from sunflower lecithin) to boost absorption. When the active ingredient is wrapped in a protective layer of fatty acids, it’s easier for your body to digest the active ingredient. Instead of losing the spermidine to your stomach acid, you can absorb the highest possible dose as the fatty layers protect it until it reaches its intended destination.
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Top 3 Benefits of Liposomal Delivery System
There are other spermidine supplements available today. However, GenuinePurity Spermidine is unique because it uses a liposomal delivery system.
Here are the three main benefits of the liposomal delivery system, which involves wrapping the active ingredients in a fatty layer to boost absorption:
Benefit #1: Protective Shield: The fatty layers form a protective shield to safeguard the active ingredients from your stomach acid. The fatty layers surround the active ingredient as it passes through your stomach, preserving its integrity.
Benefit #2: Higher Solubility: GenuinePurity Spermidine aims to amplify solubility with the liposomal delivery system, boosting the absorption process and helping spermidine enter your bloodstream effortlessly. When it’s more soluble, it’s easier for your body to break down and absorb.
Benefit #3: Better Cellular Uptake: Liposomes boost the cellular uptake of spermidine, increasing the absorption of the active ingredient into your cells, where it can provide the full effects.
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GenuinePurity Spermidine vs. Other Spermidine Supplements
Spermidine supplements have surged in popularity in the last few years. Many people take spermidine daily for anti-aging effects. However, GenuinePurity Spermidine aims to be superior to other spermidine supplements.
Other spermidine supplements, according to GenuinePurity, are “cheap imitations” because they’re synthetic. They’re made in a lab, not from natural sources like wheat germ extract.
Making things worse, synthetic spermidine has only been tested on mice – not humans. Studies have shown some anti-aging results on mice, but syntenic spermidine has not been proven safe or effective in major human trials. In comparison, wheat germ extract has been unused for thousands of years without issues.
Some of the differences between GenuinePurity Spermidine and other spermidine supplements include:
Natural Spermidine vs. Synthetic Spermidine: GenuinePurity Spermidine uses natural spermidine from wheat germ extract, while other supplements use synthetic, lab-made spermidine.
Proven in Human Trials: Synthetic spermidine has only been tested on mice – not humans. Meanwhile, humans have used wheat germ extract successfully for thousands of years.
Potent 8mg Dose: Each serving of GenuinePurity Spermidine contains 8mg of spermidine. In comparison, many spermidine supplements only contain 3 or 5mg of spermidine. Some even contain as little as 1mg of spermidine. Most studies use doses of 5mg or higher, so the 8mg of spermidine in GenuinePurity Spermidine is particularly impressive. GenuinePurity claims this “recommended dose is safe without any negative reported side-effects.”
Liposomal Delivery System for Better Absorption: One of the most significant advantages of GenuinePurity Spermidine is using a liposomal delivery system, including fatty acids derived from sunflowers, to promote better absorption. Studies show your body doesn’t absorb spermidine well on its own. Instead of losing spermidine to stomach acid, you can rely on the liposomal delivery system to protect the active ingredients until they reach their intended destination.
Lab Tested: GenuinePurity not only tests its supplement in a lab to verify purity and potency but also shares those test results online for anyone to see. You can view the latest lab test results here to check the purity, potency, and dosage of GenuinePurity Spermidine to verify it matches the label.
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Scientific Evidence for GenuinePurity Spermidine
GenuinePurity cites ample scientific evidence proving Spermidine works as advertised to promote longevity, cellular renewal, and other effects. We’ll review some of the science behind the formula below.
A 2021 study analyzed the effects of spermidine on aging and age-related diseases. Researchers were searching for anti-aging ingredients to address the rise of age-related diseases among elderly populations and the related socio-economic challenges linked to these diseases. Researchers found spermidine modulated aging, suppressing the occurrence of age-related diseases and their severity, thereby prolonging lifespan. Researchers found a link between spermidine and longevity, although they did not determine the precise mechanisms explaining why spermidine works.
In a 2024 study, researchers sought to determine those exact mechanisms and determine why spermidine works for anti-aging. Researchers found spermidine prolongs the lifespan of fungi, nematodes, insects, and rodents while also postponing age-related disorders like cardiovascular disease and neurodegeneration. Researchers believe these effects were linked to multiple biological mechanisms. Namely, some diseases appear to be related to elevated polyamine levels, and taking a polyamine supplement could help.
Researchers recently published a trial analyzing how spermidine could extend lifespans in multiple organisms, including yeast, nematodes, flies, and mice. Researchers found organisms that consumed more spermidine in their diet tended to live longer than those with lower amounts of spermidine.
The liposomal delivery system in GenuinePurity Spermidine is essential for absorption. Studies show simply taking spermidine directly doesn’t raise spermidine in your blood or saliva. In a 2024 study published in Nutrients, researchers found that non-liposomal spermidine supplements, even at high doses, did not increase spermidine levels in blood plasma or saliva in a group of healthy adults in a double-blind, placebo-controlled setting. By wrapping spermidine in a fatty layer, GenuinePurity can increase absorption, leading to better results.
GenuinePurity Spermidine is a science-backed supplement featuring a strong dose of a single active ingredient. Multiple studies have connected spermidine to anti-aging benefits, and we’re learning more about spermidine with every study that comes out.
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GenuinePurity Spermidine Supplement Facts Label
GenuinePurity publishes its entire Supplement Facts label upfront, making it easy to see exactly what’s inside the supplement and how it works.
There’s a single active ingredient in GenuinePurity Spermidine: 99% pure spermidine. Essential inactive ingredients, including a phospholipid complex, also exist for maximum absorption.
Here are all the active and inactive ingredients in each two-capsule serving of GenuinePurity Spermidine:
8mg of spermidine (from wheat germ extract)
Other (inactive) ingredients, including vegetable cellulose (to form the capsule), microcrystalline cellulose, phospholipid complex (with sunflower lecithin and phosphatidylcholine), silicon dioxide, and vegetable stearate
Ordering GenuinePurity Spermidine
GenuinePurity Spermidine is available online from the official website and is backed by a 97-day money-back guarantee. All orders come with free shipping.
Here’s how much you pay when ordering GenuinePurity Spermidine online today:
- Order one bottle for $59.95
- Order three bottles for $159.95 ($53.32 Per Bottle)
- Order six bottles for $259.95 ($43.32 Per Bottle)
Each bottle contains 30 servings (60 capsules). You take two capsules of GenuinePurity Spermidine daily to promote autophagy and cellular renewal.
GenuinePurity Spermidine Refund Policy
GenuinePurity provides a 97-day money-back guarantee on all supplements, including Spermidine. You have 97 days to try the supplement, decide if you like it, and request a refund if you’re unhappy for any reason.
You won’t find a better deal on GenuinePurity Spermidine anywhere else!
About GenuinePurity
GenuinePurity is a health and wellness company offering a range of supplements. The company is best known for its anti-aging formulas, including Resveratrol and Spermidine.
GenuinePurity is a Leading Edge Health subsidiary that maintains registered addresses in British Columbia, Tennessee, and Cyprus.
GenuinePurity manufactures Spermidine in a cGMP-certified facility in the United States.
You can contact the GenuinePurity customer service team for questions, concerns, or refund requests via the following:
- Online Form: https://spermidine.genuinepurity.com/contact/
- Phone (Toll-Free): 1-866-968-6643
- Phone (International): 1-778-770-2961
- Mailing Address: 300 – 1095 McKenzie Avenue Victoria, BC V8P 2L5
Final Word
GenuinePurity Spermidine is an anti-aging supplement featuring 99% pure spermidine.
By taking two capsules of GenuinePurity Spermidine daily, you can support anti-aging benefits by inducing autophagy and increasing renewal at the cellular level.
